In the Infected Trilogy, he reported to Murray Longworth and supported Margaret Montoya in her investigation the outbreak of the Triangles. Otto and Montoya developed a romantic relationship and were married sometime before the events of PANDEMIC occurred.
Clarence served in the Army Rangers, then in the special forces. He was recruited into the CIA. After the events of Pandemic, he joined the Department of Special Threats as a field agent reporting directly to DST Director Tim Feely.