Central Intelligence Agency, Special Activities Division: 1994-1998
Central Intelligence Agency Deputy Director: 1999-2006
In the novels Infected and Contagious, Longworth held the position of Deputy Director for the U.S. Central Intelligence Agency (CIA).
Central Intelligence Agency Director: 2006-2010
In the novel Ancestor, Longworth held the position of Director for the CIA and headed up the Special Threats unit. It was revealed in Ancestor that Longworth had previously worked with Patrick O'Doyle and wanted him included in a Special Forces unit assigned to Special Threats.
Director of the Department of Special Threats: 2011-2014
In the novel Pandemic, Longworth is the director of the Department of Special Threats.
Murray retired in 2014, at the close of Pandemic, when the position of director was taken over by Tim Feely.